Pleural mesothelioma is an aggressive cancer arising from the mesothelial cells lining the pleura and can be broadly categorised by their cell type, or histology
Epithelioid: Mesothelioma tumours made up of epithelioid cells are the most common, accounting for 50-70% of all diagnoses. It is the most treatable and patients with this cell type have the best prognosis.
Sarcomatoid: The least common cell type, sarcomatoid mesothelioma accounts for approximately 15% of all mesothelioma diagnoses and has fewer treatment options than other cell types. Sarcomatoid mesothelioma is the most aggressive form of the disease and patients diagnosed with this cell type have the least favourable prognosis.
Biphasic (mixed): Mesothelioma tumours made up of both epithelioid and sarcomatoid cells are called biphasic. This subtype accounts for ~30% of all pleural mesothelioma cases and is associated with poor prognosis.
Like other cancers, pleural mesothelioma starts in a small area (the lungs/chest) and can spread to other parts of the body via the bloodstream or lymphatic system.1 Pleural mesothelioma often goes undetected until it reaches an advanced stage, as the malignancies (tumours) commonly cause non-specific symptoms that mimic other conditions such as metastatic adenocarcinoma (a form of lung cancer) which can lead to misdiagnosis or delayed detection. The median survival of patients with pleural mesothelioma is less than 12 months
WHAT IS PLEURAL MESOTHELIOMA?
Diposkan Oleh: ABD KADIR Rusdi